Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727657 | 0.89 | CNR1 (0.54) | CNR1FAAHHTR1AHTR2ADRD3 | |
| SCHEMBL1728049 | 0.86 | DRD4 (0.51) | CNR1FAAHHTR1AHTR2ADRD3 | |
| SCHEMBL1728645 | 0.86 | CNR1 (0.50) | CNR1HTR1AHTR2ADRD3DRD2 | |
| SCHEMBL1727631 | 0.83 | HTR1A (0.48) | HTR1AHTR2ADRD3DRD2DRD4 | |
| SCHEMBL14796921 | 0.83 | CHRM4 (0.48) | CNR1FAAH | |
| SCHEMBL1729632 | 0.80 | CNR1 (0.51) | CNR1HTR1AHTR2ADRD3DRD2 | |
| SCHEMBL1727960 | 0.80 | DRD4 (0.56) | CNR1HTR1AHTR2ADRD3MAPT | |
| SCHEMBL1729132 | 0.80 | DRD4 (0.52) | HTR1AHTR2ADRD3MAPTTP53 | |
| SCHEMBL1727394 | 0.78 | HTR1A (0.46) | CNR1HTR1AHTR2ADRD3DRD2 | |
| SCHEMBL1728979 | 0.77 | HTR1A (0.43) | CNR1FAAHHTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |