Sugi Predict

Sugi Predict / Compounds / SCHEMBL17283240

SCHEMBL17283240

SCHEMBL17283240

C[Si]1(C)c2ccccc2N(c2ccc(-c3nc4cc5oc(-c6ccc(N7c8ccccc8[Si](C)(C)c8ccccc87)cc6)nc5cc4o3)cc2)c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 10/20 0.45
▸ RAB9A P51151 10/20 0.45
▸ SMN1; SMN2 Q16637 9/20 0.45
▸ KDM4E B2RXH2 6/20 0.45
▸ HPGD P15428 5/20 0.45
▸ CASP3 P42574 3/20 0.45
▸ SENP7 Q9BQF6 3/20 0.45
▸ SENP6 Q9GZR1 3/20 0.45
▸ POLB P06746 2/20 0.45
▸ SENP8 Q96LD8 2/20 0.45
▸ ALDH1A1 P00352 5/20 0.40
▸ TP53 P04637 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ NFKB2 Q00653 1/20 0.40
▸ RELA Q04206 1/20 0.40
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283344 0.99 SMN1; SMN2 (0.47) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17404429 0.96 NPC1 (0.44) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283267 0.93 NPC1 (0.42) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL20383149 0.90 NPC1 (0.57) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18680433 0.88 NPC1 (0.43) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283342 0.86 SMN1; SMN2 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283236 0.86 NPC1 (0.51) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18680446 0.86 SMN1; SMN2 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283341 0.85 NPC1 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17404425 0.83 NPC1 (0.48) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 — — US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 — — US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 — — US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 — — US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 — — US disclosed
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-02 — — US disclosed
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 — — US disclosed
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 — — US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 — — US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 — — US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 — — US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 — — US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 — — US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 — — US disclosed
WO-2015176981-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2015-11-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME ODC1, KCNC1, KCNH1 NPC1 2022/4885RAB9A 1832/4885SMN1; SMN2 4209/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same ODC1, KCNC1, KCNH1 NPC1 2022/4885RAB9A 1832/4885SMN1; SMN2 4209/4885
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE DDT, DRD1, DRD2 NPC1 3198/4885RAB9A 1696/4885SMN1; SMN2 4840/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.