Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 11/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | USP5 | P45974 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922931 | 0.89 | USP14 (0.49) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17286130 | 0.84 | USP14 (0.40) | USP14SMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL17286129 | 0.83 | RAB9A (0.45) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19749200 | 0.80 | USP14 (0.49) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6923190 | 0.80 | USP14 (0.47) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19501342 | 0.80 | SMN1; SMN2 (0.60) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17949746 | 0.78 | USP14 (0.61) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6923276 | 0.77 | ALDH1A1 (0.50) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6922806 | 0.76 | SMN1; SMN2 (0.48) | USP14HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6923174 | 0.75 | SMN1; SMN2 (0.63) | USP14HTTSMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150335652-A1 | USP14 Inhibitors for Treating or Preventing Viral Infections | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335652-A1 | USP14 Inhibitors for Treating or Preventing Viral Infections | USP14, USP1, USP13 | USP14 1/4885HTT 3270/4885SMN1; SMN2 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.