Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 6/20 | 0.43 |
| ▸ | SKP1 | P63208 | 6/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730203 | 0.88 | CHRM4 (0.51) | MALT1KMT2ACHRM4 | |
| SCHEMBL1727773 | 0.83 | P2RX7 (0.54) | MALT1KMT2AP2RX7LDHACKS1B | |
| SCHEMBL3270076 | 0.82 | MALT1 (0.42) | MALT1KMT2AP2RX7LDHACKS1B | |
| SCHEMBL1727869 | 0.82 | KDM4E (0.62) | MALT1P2RX7LDHAKDM4EALDH1A1 | |
| SCHEMBL1728915 | 0.81 | KMT2A (0.50) | MALT1KMT2AKDM4EALDH1A1TRPV1 | |
| SCHEMBL1727778 | 0.79 | P2RX7 (0.53) | KMT2AP2RX7LDHACKS1BSKP1 | |
| SCHEMBL1728699 | 0.79 | HRH4 (0.51) | MALT1CKS1BSKP1SKP2KDM4E | |
| SCHEMBL4879872 | 0.79 | KDM4E (0.60) | MALT1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22776419 | 0.78 | ALDH1A1 (0.52) | CKS1BSKP1SKP2KDM4EALDH1A1 | |
| SCHEMBL4304306 | 0.76 | ABL1 (0.48) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |