Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286709 | 0.83 | ESR1 (0.45) | HSD11B1ESR1ESR2CYP1A2CYP2C9 | |
| SCHEMBL10046766 | 0.80 | CYP2C19 (0.51) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31603748 | 0.80 | CYP2C19 (0.51) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10685591 | 0.80 | ALOX15 (0.50) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30688233 | 0.80 | ALOX15 (0.50) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17286706 | 0.79 | HSD11B1 (0.40) | HSD11B1CYP2C9CYP2C19PGR | |
| SCHEMBL9863223 | 0.74 | ALOX15 (0.53) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10046743 | 0.74 | CYP2C19 (0.49) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17269273 | 0.74 | CYP3A4 (0.46) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL20958248 | 0.72 | GABRA1 (0.46) | HSD11B1ESR1ESR2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464163-B2 | Novolak resin containing hexafluoroisopropanol group, method for producing same, and composition of same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20150337077-A1 | Novolak Resin Containing Hexafluoroisopropanol Group, Method for Producing Same, and Composition of Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-26 | — | — | US | disclosed |