Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286718 | 0.85 | HSD11B1 (0.42) | HSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL13452244 | 0.80 | DHFR (0.41) | DHFRALDH1A1CYP2C19CYP2C9NR3C1 | |
| SCHEMBL17286705 | 0.79 | HSD11B1 (0.42) | HSD11B1CYP2C19CYP2C9PGR | |
| SCHEMBL17072152 | 0.77 | DHFR (0.40) | DHFRALDH1A1CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL20987916 | 0.73 | CYP3A4 (0.37) | DHFRALDH1A1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL25596263 | 0.73 | HSD11B1 (0.34) | HSD11B1LMNA | |
| SCHEMBL14999487 | 0.70 | PTGS2 (0.39) | DHFRALDH1A1CYP2C19CYP2C9LMNA | |
| SCHEMBL13310100 | 0.70 | DHFR (0.44) | DHFRALDH1A1CYP2C19PGRNR3C1 | |
| SCHEMBL13707222 | 0.70 | CYP2C19 (0.41) | DHFRALDH1A1CYP2C19CYP2C9LMNA | |
| SCHEMBL17286719 | 0.69 | ACHE (0.35) | HSD11B1ALDH1A1PGRNR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464163-B2 | Novolak resin containing hexafluoroisopropanol group, method for producing same, and composition of same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20150337077-A1 | Novolak Resin Containing Hexafluoroisopropanol Group, Method for Producing Same, and Composition of Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-26 | — | — | US | disclosed |