SCHEMBL1728678

SCHEMBL1728678

O=C1OCc2cccnc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
TDP2 O95551 2/20 0.43
NSD2 O96028 2/20 0.43
PAX8 Q06710 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
GAA P10253 2/20 0.43
ABL1 P00519 1/20 0.43
PLCG1 P19174 1/20 0.43
CES1 P23141 1/20 0.43
RIN1 Q13671 1/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TYMS P04818 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28536193 0.80 GSK3A (0.36) MAOAMAOBNSD2KDM4EALDH1A1
SCHEMBL7000587 0.77 MAOB (0.54) MAOAMAOBTDP2NSD2PAX8
SCHEMBL11992046 0.76 TDP1 (0.38) TDP2NSD2PAX8TDP1GAA
SCHEMBL4507981 0.73 MAOB (0.43) MAOBTDP2NSD2PAX8TDP1
SCHEMBL29606008 0.73 MAOB (0.43) MAOBTDP2NSD2PAX8TDP1
SCHEMBL22990892 0.72 TDP2 (0.50) MAOAMAOBTDP2NSD2PAX8
Hydrochloric Acid SCHEMBL4501139 0.72 MAOB (0.42) MAOBTDP2NSD2PAX8TDP1
SCHEMBL4050960 0.71 MAPT (0.63) MAOBTDP2NSD2PAX8TDP1
SCHEMBL6998860 0.71 FNTA (0.49) MAOAMAOBMEN1KMT2ACDC25B
SCHEMBL27200082 0.71 KMT2A (0.36) MAOAMAOBTDP2NSD2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101583876-A Chemical indicator test strip 3M INNOVATIVE PROPERTIES CO (US) 2009-11-18 CN claimed
US-4564679-A AZAPHTHALIDES YAMADA CHEMICAL CO., LTD. (JP) 1986-01-14 US claimed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US claimed
JP-5139026-A None JP disclosed
JP-56151597-A None JP disclosed
JP-7278451-A None JP disclosed
EP-4744902-A1 ON-PRESS DEVELOPMENT-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, PLANOGRAPHIC PRINTING PLATE PRODUCTION METHOD, AND PLANOGRAPHIC PRINTING METHO FUJIFILM Corporation (JP) 2026-05-20 EP disclosed
EP-4744901-A1 ON-PRESS DEVELOPMENT TYPE PLANOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING METHOD, AND COMPOUND FUJIFILM Corporation (JP) 2026-05-20 EP disclosed
US-20260131566-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2026-05-14 US disclosed
US-20260131567-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING METHOD, AND COMPOUND FUJIFILM CORPORATION (JP) 2026-05-14 US disclosed
EP-4186708-B1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING A LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORP (JP) 2026-03-04 EP disclosed
US-4660060-A COLOR-FORMING FOR TRANSFER IMAGING; XEROGRAPHY THE HILTON-DAVIS CHEMICAL CO. (US) 1987-04-21 US disclosed
EP-0206114-A2 Novel substituted phthalides and furopyridinones, preparation thereof and use thereof as color formers HILTON-DAVIS CHEMICAL CO. (US) 1986-12-30 EP disclosed
US-4587539-A Chromogenic dihydrofuropyridinones CIBA-GEIGY CORPORATION (US) 1986-05-06 US disclosed
US-4564679-A AZAPHTHALIDES YAMADA CHEMICAL CO., LTD. (JP) 1986-01-14 US disclosed
US-4508897-A CONDENSATION OF AN ANILINE AND THE PRODUCT OF A QUINOLINIC ANHYDRI CIBA GEIGY CORPORATION (US) 1985-04-02 US disclosed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
JP-S56151597-A RECORDING MATERIAL YAMAMOTO KAGAKU GOSEI KK 1981-11-24 JP disclosed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131567-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING METHOD, AND COMPOUND LEF1, LARP1, RUVBL1 MAOA 4264/4885MAOB 4306/4885TDP2 4247/4885
US-20260131566-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD LAMTOR3, LEF1, RER1 MAOA 4515/4885MAOB 4490/4885TDP2 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.