Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287122 | 0.80 | IRAK4 (0.38) | TK1MAOAFBP1 | |
| SCHEMBL10504741 | 0.78 | CA2 (0.42) | CA2HTR2BMAOAGRM2MAPT | |
| SCHEMBL22245078 | 0.77 | FBP1 (0.36) | TK1MAOAGRM2FBP1 | |
| SCHEMBL9489070 | 0.76 | HTR2B (0.46) | CA2HTR2BMAOAMAPT | |
| SCHEMBL10368362 | 0.75 | CA2 (0.47) | CA2HTR2BMAOAGRM2MAPT | |
| SCHEMBL14183559 | 0.75 | CA2 (0.47) | CA2HTR2BMAOAGRM2MAPT | |
| SCHEMBL24225587 | 0.71 | GRM2 (0.63) | CA2HTR2BGRM2 | |
| SCHEMBL10504552 | 0.71 | NPC1 (0.50) | CA2HTR2BGRM2 | |
| SCHEMBL10504542 | 0.71 | NPC1 (0.50) | CA2HTR2BGRM2 | |
| SCHEMBL22238932 | 0.70 | TK1 (0.32) | TK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | OXA1L, XDH, MYD88 | CA2 2803/4885HTR2B 4711/4885TK1 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.