Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727572 | 0.92 | CNR1 (0.41) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1729255 | 0.90 | HTR1A (0.43) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727605 | 0.83 | DGAT1 (0.44) | HTR1ADRD4HTR2ADRD3CKS1B | |
| SCHEMBL1729052 | 0.82 | NPC1 (0.43) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2407375 | 0.82 | CKS1B (0.40) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727912 | 0.82 | CNR1 (0.42) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727546 | 0.82 | HSD11B1 (0.39) | DRD2DRD3CKS1BSKP1SKP2 | |
| SCHEMBL2407202 | 0.82 | CKS1B (0.40) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2405880 | 0.82 | CKS1B (0.40) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1728840 | 0.79 | HTR1A (0.39) | HTR1ADRD2HTR7CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |