SCHEMBL17288560

SCHEMBL17288560

[CH2]c1ccc2cccc(F)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 2/20 0.41
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ AHR P35869 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP2A6 P11509 3/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP1B1 Q16678 4/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ CA12 O43570 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ CYP1A2 P05177 5/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ PTGER3 P43115 2/20 0.32
▸ CYP1A1 P04798 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7834989 0.83 HSD17B1 (0.38) HPRT1MEN1KMT2AMAPTRAB9A
SCHEMBL1458869 0.77 CYP2A6 (0.52) HPRT1MEN1KMT2AMAPTRAB9A
SCHEMBL31257785 0.76 ALDH1A1 (0.43) HPRT1MEN1KMT2AMAPTRAB9A
SCHEMBL1971712 0.75 ALDH1A1 (0.64) HPRT1MAPTAHRCYP2A6ALDH1A1
SCHEMBL4610309 0.74 CTDSP1 (0.59) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL6488242 0.74 CYP2A6 (0.63) HPRT1MEN1KMT2AMAPTRAB9A
SCHEMBL7835630 0.74 ALDH1A1 (0.54) HPRT1MEN1KMT2AMAPTRAB9A
SCHEMBL17289126 0.74 CYP2A6 (0.54) MEN1KMT2AMAPTAHRCYP2A6
SCHEMBL4302977 0.74 CYP2A6 (0.48) HPRT1MEN1KMT2AMAPTAHR
SCHEMBL4542359 0.74 KDM4E (0.57) MEN1KMT2AMAPTRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 — — EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 — — EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 — — US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 — — US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 — — EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 HPRT1 3218/4885MEN1 2787/4885KMT2A 393/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 HPRT1 4600/4885MEN1 4523/4885KMT2A 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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