Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615296 | 0.91 | TNKS (0.47) | TNKSPARP1TNKS2AURKACYP1A2 | |
| SCHEMBL30222750 | 0.90 | CHRNB2 (0.49) | TNKSPARP1TNKS2CHRNB2CHRNA4 | |
| SCHEMBL21852879 | 0.87 | CXCR4 (0.51) | TNKSPARP1TNKS2KMT2AALOX15 | |
| SCHEMBL3148862 | 0.87 | CXCR4 (0.50) | TNKSPARP1TNKS2SCN9AKMT2A | |
| SCHEMBL20329139 | 0.86 | TNKS (0.40) | TNKSPARP1TNKS2CHRNB2CHRNA4 | |
| SCHEMBL18705070 | 0.86 | HRH3 (0.47) | TNKSPARP1TNKS2SCN9AAURKA | |
| SCHEMBL20859274 | 0.85 | CHKA (0.47) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL21043992 | 0.85 | KDM4E (0.43) | TNKSPARP1TNKS2KDM4EMGLL | |
| SCHEMBL22432752 | 0.84 | SCN9A (0.42) | TNKSPARP1TNKS2SCN9AKMT2A | |
| SCHEMBL15014498 | 0.84 | ALDH1A1 (0.49) | TNKSPARP1TNKS2SCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610269-A1 | UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE | 3B Pharmaceuticals GmbH (DE) | 2025-09-03 | — | — | EP | disclosed |
| US-10450336-B2 | Nitrogen-rich macrocyclic ligands, chelation complexes thereof, and process for selective chelation of radioactive bismuth ions with the ligands | TRIAD NATIONAL SECURITY, LLC (US) | 2019-10-22 | — | — | US | disclosed |
| US-10450336-B2 | Nitrogen-rich macrocyclic ligands, chelation complexes thereof, and process for selective chelation of radioactive bismuth ions with the ligands | TRIAD NATIONAL SECURITY, LLC (US) | 2019-10-22 | — | — | US | disclosed |
| US-20150344508-A1 | NITROGEN-RICH MACROCYCLIC LIGANDS, CHELATION COMPLEXES THEREOF, AND PROCESS FOR SELECTIVE CHELATION OF RADIOACTIVE BISMUTH IONS WITH THE LIGANDS | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344508-A1 | NITROGEN-RICH MACROCYCLIC LIGANDS, CHELATION COMPLEXES THEREOF, AND PROCESS FOR SELECTIVE CHELATION OF RADIOACTIVE BISMUTH IONS WITH THE LIGANDS | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344508-A1 | NITROGEN-RICH MACROCYCLIC LIGANDS, CHELATION COMPLEXES THEREOF, AND PROCESS FOR SELECTIVE CHELATION OF RADIOACTIVE BISMUTH IONS WITH THE LIGANDS | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450336-B2 | Nitrogen-rich macrocyclic ligands, chelation complexes thereof, and process for selective chelation of radioactive bismuth ions with the ligands | NCL, NCLN, POLH | TNKS 1539/4885PARP1 1618/4885TNKS2 2531/4885 |
| US-20150344508-A1 | NITROGEN-RICH MACROCYCLIC LIGANDS, CHELATION COMPLEXES THEREOF, AND PROCESS FOR SELECTIVE CHELATION OF RADIOACTIVE BISMUTH IONS WITH THE LIGANDS | NCL, NCLN, POLH | TNKS 1539/4885PARP1 1618/4885TNKS2 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.