SCHEMBL21043992

SCHEMBL21043992

O=C(O)CN1CCN(CC(=O)O)CCN(Cc2cnccn2)CCN(CC(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 6/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TNKS O95271 1/20 0.41
PARP1 P09874 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
MGLL Q99685 2/20 0.40
KDM5C P41229 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SRPK1 Q96SB4 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2D6 P10635 1/20 0.39
GFER P55789 2/20 0.39
WNT1 P04628 1/20 0.39
GSK3B P49841 1/20 0.39
DYRK1A Q13627 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17289014 0.85 TNKS (0.46) KDM4EALDH1A1NPSR1TNKSPARP1
SCHEMBL21207066 0.79 L3MBTL1 (0.64) KDM4EALDH1A1L3MBTL1CYP2D6WNT1
SCHEMBL26969150 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL30811211 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL30218423 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL8211724 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL21044013 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL8209027 0.78 KDM4E (0.68) KDM4EALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL16615296 0.77 TNKS (0.47) KDM4ETNKSPARP1TNKS2CYP2D6
SCHEMBL30222750 0.76 CHRNB2 (0.49) TNKSPARP1TNKS2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN claimed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US claimed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN claimed
EP-4127255-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Technologies, LLC (US) 2023-02-08 EP claimed
EP-3717466-B1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2022-01-05 EP claimed
EP-3717466-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2020-10-07 EP claimed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US claimed
EP-3492460-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2019-06-05 EP claimed
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2025-07-17 US disclosed
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR. V.V.I. (CZ) 2025-04-08 US disclosed
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN disclosed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US disclosed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN disclosed
EP-4127255-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Technologies, LLC (US) 2023-02-08 EP disclosed
EP-3717466-B1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2022-01-05 EP disclosed
WO-2021202914-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Medical Technologies, LLC (US) 2021-10-07 WO disclosed
EP-3717466-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2020-10-07 EP disclosed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US disclosed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US disclosed
EP-3492460-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2019-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCO2, SOD3, SLC39A3 KDM4E 4827/4885ALDH1A1 4085/4885NPSR1 322/4885
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCLY, SFXN1, PTCD3 KDM4E 4511/4885ALDH1A1 2634/4885NPSR1 603/4885
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof SCLY, SFXN1, PTCD3 KDM4E 4511/4885ALDH1A1 2634/4885NPSR1 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.