Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960907 | 0.88 | KMT2A (0.62) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL30141105 | 0.88 | KMT2A (0.62) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL4403626 | 0.84 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL10861035 | 0.84 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL4279981 | 0.82 | HSD17B10 (0.61) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL3245222 | 0.81 | SMPD1 (0.67) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL10861040 | 0.81 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL2087641 | 0.81 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL873776 | 0.81 | SMPD1 (0.70) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL29556736 | 0.81 | MRGPRX4 (0.62) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387596-A1 | BIODEGRADABLE HYDROGEL AND METHODS FOR USE THEREOF | INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY (SG) | 2022-12-08 | — | — | US | disclosed |
| US-11478550-B2 | Biodegradable hydrogel and methods for use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-10-25 | — | — | US | disclosed |
| US-20200155686-A1 | BIODEGRADABLE HYDROGEL AND METHODS FOR USE THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-05-21 | — | — | US | disclosed |
| WO-2019059850-A1 | NANOPARTICLE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-28 | — | — | WO | disclosed |
| US-20170266224-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-09-21 | — | — | US | disclosed |
| US-20170266224-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-09-21 | — | — | US | disclosed |
| US-9682100-B2 | Cationic polyamines for treatment of viruses | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682100-B2 | Cationic polyamines for treatment of viruses | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160213707-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-07-28 | — | — | US | disclosed |
| US-20160213707-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-07-28 | — | — | US | disclosed |
| US-9399044-B2 | Antimicrobial cationic polyamines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155686-A1 | BIODEGRADABLE HYDROGEL AND METHODS FOR USE THEREOF | HPGDS, TBCA, HLCS | NPC1 2421/4885RAB9A 3551/4885SMN1; SMN2 4181/4885 |
| US-11478550-B2 | Biodegradable hydrogel and methods for use thereof | HPGDS, TBCA, HLCS | NPC1 2421/4885RAB9A 3551/4885SMN1; SMN2 4181/4885 |
| US-20160213707-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | PARG, PIGO, M6PR | NPC1 1324/4885RAB9A 3187/4885SMN1; SMN2 908/4885 |
| US-20220387596-A1 | BIODEGRADABLE HYDROGEL AND METHODS FOR USE THEREOF | HPGDS, TBCA, HLCS | NPC1 2421/4885RAB9A 3551/4885SMN1; SMN2 4181/4885 |
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | ARG1, PARG, ARG2 | NPC1 2187/4885RAB9A 3141/4885SMN1; SMN2 3525/4885 |
| US-20170266224-A1 | CATIONIC POLYAMINES FOR TREATMENT OF VIRUSES | PARG, PIGO, M6PR | NPC1 1324/4885RAB9A 3187/4885SMN1; SMN2 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.