SCHEMBL17289293

SCHEMBL17289293

CNCCNC(=O)C1(C)CCc2c(C)c(O)c(C)c(C)c2O1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.65
PTGS2 P35354 1/20 0.65
CYP1A2 P05177 1/20 0.65
CYP3A4 P08684 1/20 0.65
TSHR P16473 1/20 0.65
ACHE P22303 17/20 0.56
BCHE P06276 16/20 0.56
MAOB P27338 1/20 0.52
TTPA P49638 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058902 0.88 PTGS1 (0.67) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL2059248 0.88 PTGS1 (0.67) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL2059215 0.88 PTGS1 (0.67) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL2058898 0.88 PTGS1 (0.67) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL24002493 0.88 PTGS1 (0.62) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL15820257 0.87 PTGS1 (0.65) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL15426762 0.87 PTGS1 (0.65) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL29670762 0.87 PTGS1 (0.65) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL2059291 0.87 PTGS1 (0.68) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL26169544 0.86 PTGS1 (0.61) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180170892-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAGAMAGE SULFATEQ B.V. (NL) 2018-06-21 US claimed
EP-3297625-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE Sulfateq B.V. (NL) 2018-03-28 EP claimed
US-20170151234-A1 6-Hydroxy-2,5,7,8-Tetramethylchroman-Compounds for the Treatment of Chronic Obstructive Airway Diseases SULFATEQ B.V. (NL) 2017-06-01 US claimed
EP-3157518-A1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES Sulfateq B.V. (NL) 2017-04-26 EP claimed
WO-2016188766-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE SULFATEQ B.V. (NL) 2016-12-01 WO claimed
WO-2015193365-A1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES SULFATEQ B.V. (NL) 2015-12-23 WO claimed
EP-3388426-B1 COMPOUNDS FOR PROTECTION OF CELLS SULFATEQ BV (NL) 2023-07-05 EP disclosed
US-20230160001-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-05-25 US disclosed
US-20210227822-A1 COMPOUNDS FOR PROTECTION OF CELLS SULFATEQ B.V. (NL) 2021-07-29 US disclosed
US-11006626-B2 Compounds for protection of cells SULFATEQ B.V. (NL) 2021-05-18 US disclosed
CN-107660148-B Compounds for preventing or treating organ damage 萨尔法泰克有限公司 2021-03-09 CN disclosed
US-20210024485-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE SULFATEQ B.V. (NL) 2021-01-28 US disclosed
US-10676452-B2 Compound for the prophylaxis or treatment of organ damage SULFATEQ B.V. (NL) 2020-06-09 US disclosed
EP-3297625-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE Sulfateq B.V. (NL) 2018-03-28 EP disclosed
US-9913841-B2 6-hydroxy-2,5,7,8-tetramethylchroman-compounds for the treatment of chronic obstructive airway diseases SULFATEQ B.V. (NL) 2018-03-13 US disclosed
US-20170151234-A1 6-Hydroxy-2,5,7,8-Tetramethylchroman-Compounds for the Treatment of Chronic Obstructive Airway Diseases SULFATEQ B.V. (NL) 2017-06-01 US disclosed
EP-3157518-A1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES Sulfateq B.V. (NL) 2017-04-26 EP disclosed
WO-2016188766-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE SULFATEQ B.V. (NL) 2016-12-01 WO disclosed
WO-2015193365-A1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES SULFATEQ B.V. (NL) 2015-12-23 WO disclosed
US-20150342174-A1 COMPOUNDS FOR PROTECTION OF CELLS SULFATEQ B.V. (NL) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170151234-A1 6-Hydroxy-2,5,7,8-Tetramethylchroman-Compounds for the Treatment of Chronic Obstructive Airway Diseases HRH4, CFTR, HRH2 PTGS1 211/4885PTGS2 84/4885CYP1A2 361/4885
US-11006626-B2 Compounds for protection of cells CASP10, BAX, CASP9 PTGS1 1184/4885PTGS2 1395/4885CYP1A2 3066/4885
US-20210227822-A1 COMPOUNDS FOR PROTECTION OF CELLS CASP10, BAX, CASP9 PTGS1 1184/4885PTGS2 1395/4885CYP1A2 3066/4885
US-10676452-B2 Compound for the prophylaxis or treatment of organ damage GLS, TXN2, SLC5A2 PTGS1 119/4885PTGS2 190/4885CYP1A2 1122/4885
US-20210024485-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE GLS, TXN2, SLC5A2 PTGS1 119/4885PTGS2 190/4885CYP1A2 1122/4885
US-20150342174-A1 COMPOUNDS FOR PROTECTION OF CELLS CASP10, BAX, CASP9 PTGS1 1184/4885PTGS2 1395/4885CYP1A2 3066/4885
US-20180170892-A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAGAMAGE LIPG, GLS, TXN2 PTGS1 75/4885PTGS2 109/4885CYP1A2 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.