Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 8/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729043 | 0.89 | EGLN1 (0.41) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729085 | 0.88 | RET (0.41) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729147 | 0.87 | MGLL (0.43) | DRD2DRD4MGLLHTR1AHTR2A | |
| SCHEMBL1728057 | 0.86 | MCHR1 (0.42) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1727560 | 0.85 | KCNH2 (0.42) | MGLLEGLN1 | |
| SCHEMBL1730213 | 0.83 | DRD4 (0.47) | DRD2DRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1727691 | 0.83 | CNR1 (0.41) | DRD2DRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1728914 | 0.82 | MCHR1 (0.44) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729203 | 0.81 | GRIN1 (0.42) | DRD4MGLLHTR1AHTR2ADRD3 | |
| SCHEMBL1727880 | 0.77 | CNR2 (0.50) | DRD2DRD4MGLLHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |