Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.38 |
| ▸ | ME1 | P48163 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727880 | 0.89 | CNR2 (0.50) | MGLLDRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1728997 | 0.87 | DRD2 (0.42) | MGLLDRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1727895 | 0.87 | EGLN1 (0.43) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729278 | 0.87 | HTR1A (0.41) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729017 | 0.85 | DRD3 (0.42) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1729061 | 0.84 | DGAT1 (0.46) | MGLLAOC3EGLN1CNR2DGAT1 | |
| SCHEMBL1728979 | 0.82 | HTR1A (0.43) | DRD4HTR1AHTR2ADRD3DRD2 | |
| SCHEMBL1730270 | 0.81 | EGLN1 (0.47) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1730237 | 0.81 | MCHR1 (0.44) | DRD4HTR1AHTR2ADRD3SLC6A4 | |
| SCHEMBL1728819 | 0.80 | SLC6A7 (0.43) | MGLLDRD4HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |