Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729203 | 0.91 | GRIN1 (0.42) | MCHR1HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1729043 | 0.90 | EGLN1 (0.41) | HRH2HRH1HTR1ADRD4HTR2A | |
| SCHEMBL1729017 | 0.88 | DRD3 (0.42) | MCHR1HRH2HRH1HTR1ADRD4 | |
| SCHEMBL1728997 | 0.86 | DRD2 (0.42) | HTR1ADRD4HTR2ASLC6A4DRD3 | |
| SCHEMBL1729330 | 0.84 | MCHR1 (0.41) | MCHR1HRH2HRH1HTR1ADRD4 | |
| SCHEMBL1729085 | 0.84 | RET (0.41) | HRH2HRH1HTR1ADRD4HTR2A | |
| SCHEMBL1730213 | 0.83 | DRD4 (0.47) | HTR1ADRD4HTR2ASLC6A4DRD3 | |
| SCHEMBL13136653 | 0.81 | SLC6A4 (0.46) | MCHR1HRH2HRH1HTR1ADRD4 | |
| SCHEMBL1727526 | 0.80 | HRH2 (0.47) | MCHR1HRH2HRH1HTR1ADRD4 | |
| SCHEMBL1728819 | 0.79 | SLC6A7 (0.43) | HTR1ADRD4HTR2ASLC6A4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |