Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730213 | 0.90 | DRD4 (0.47) | EGLN1DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1728057 | 0.90 | MCHR1 (0.42) | DRD4HTR1AHTR2ASLC6A4DRD3 | |
| SCHEMBL1727895 | 0.89 | EGLN1 (0.43) | EGLN1DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1728997 | 0.89 | DRD2 (0.42) | EGLN1DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1729085 | 0.86 | RET (0.41) | EGLN1DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1730370 | 0.84 | CNR1 (0.44) | DRD4HTR1AHTR2ADRD3HSD17B10 | |
| SCHEMBL1729203 | 0.83 | GRIN1 (0.42) | DRD4HTR1AHTR2ASLC6A4DRD3 | |
| SCHEMBL1728914 | 0.81 | MCHR1 (0.44) | DRD4HTR1AHTR2ASLC6A4DRD3 | |
| SCHEMBL1730270 | 0.79 | EGLN1 (0.47) | EGLN1DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1729537 | 0.78 | DRD4 (0.55) | EGLN1DRD4PPARAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |