Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18980470 | 0.88 | DRD2 (0.52) | DRD2DRD3ADRB2NCF1PDGFRB | |
| SCHEMBL3266253 | 0.84 | SIRT2 (0.48) | DRD2DRD3SIRT2SIRT1SIRT3 | |
| SCHEMBL21034183 | 0.82 | ADRB2 (0.53) | DRD2DRD3ADRB2NCF1PDGFRB | |
| SCHEMBL3265695 | 0.82 | SIRT2 (0.45) | DRD2DRD3SIRT2SIRT1SIRT3 | |
| SCHEMBL20771438 | 0.81 | NCF1 (0.54) | SIRT2SIRT1SIRT3NCF1PDGFRB | |
| SCHEMBL14797012 | 0.81 | HTR1A (0.46) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL1728813 | 0.81 | SIRT2 (0.51) | DRD2SIRT2SIRT1SIRT3DRD4 | |
| SCHEMBL28664473 | 0.80 | ADRB2 (0.51) | DRD2DRD3ADRB2NCF1PDGFRB | |
| SCHEMBL22291150 | 0.79 | ENPP1 (0.54) | DRD2DRD3ADRB2NCF1HTR2A | |
| SCHEMBL31429462 | 0.79 | ENPP1 (0.54) | DRD2DRD3ADRB2NCF1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |