Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172828 | 0.91 | CTSL (0.34) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL13060890 | 0.80 | CTSL (0.41) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL13060892 | 0.80 | CTSL (0.41) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL172990 | 0.79 | CTSL (0.33) | CTSLCTSSCTSKUTS2RROCK2 | |
| SCHEMBL13005481 | 0.78 | CTSL (0.41) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL13005472 | 0.78 | CTSL (0.41) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL171291 | 0.77 | TDP1 (0.32) | — | |
| SCHEMBL172976 | 0.76 | HDAC4 (0.37) | HDAC4CTSLCTSSCTSKUTS2R | |
| SCHEMBL172688 | 0.74 | UTS2R (0.37) | HDAC4UTS2R | |
| SCHEMBL13060891 | 0.73 | TAS1R3 (0.44) | HDAC4CTSLCTSSCTSKTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |