Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907640 | 0.89 | AOC3 (0.70) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL804251 | 0.89 | AOC3 (0.70) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL907809 | 0.89 | AOC3 (0.70) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL7244349 | 0.87 | AOC3 (0.68) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL25101015 | 0.75 | TAAR1 (0.54) | AOC3SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL12993183 | 0.75 | AOC3 (0.68) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6320573 | 0.75 | TAAR1 (0.54) | AOC3SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL6284970 | 0.75 | AOC3 (0.68) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL31068723 | 0.75 | AOC3 (0.43) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL25263668 | 0.75 | AOC3 (0.43) | AOC3SLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940421-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-07-09 | — | — | EP | claimed |
| WO-2007032004-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | claimed |
| EP-1934234-B1 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | YISSUM RES DEV CO (IL) | 2011-11-30 | — | — | EP | disclosed |
| US-20100284914-A1 | Novel Amine-Borane Compounds and Uses Thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2010-11-11 | — | — | US | disclosed |
| US-20090131366-A1 | Use of Amine-Borane Compounds as Anti-Microbial Agents | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2009-05-21 | — | — | US | disclosed |
| EP-1940421-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-07-09 | — | — | EP | disclosed |
| EP-1934234-A2 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032004-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007032005-A2 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131366-A1 | Use of Amine-Borane Compounds as Anti-Microbial Agents | BCAT2, BCAT1, ARG1 | AOC3 135/4885SLC6A2 610/4885SLC6A4 1463/4885 |
| US-20100284914-A1 | Novel Amine-Borane Compounds and Uses Thereof | SLC1A5, BDKRB1, PAICS | AOC3 874/4885SLC6A2 340/4885SLC6A4 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.