Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729391 | 0.92 | DNM1 (0.67) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Dimethylnonylamine Cyanoborane SCHEMBL1729343 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Dimethylpentadecylamine Cyanoborane SCHEMBL1728907 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Dimethyltridecylamine Cyanoborane SCHEMBL1728054 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Dimethylundecylamine Cyanoborane SCHEMBL1727625 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Heptadecyldimethylamine Cyanoborane SCHEMBL1727494 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Dodecyldimethylamine Cyanoborane SCHEMBL1727682 | 0.90 | DNM1 (0.71) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| Water SCHEMBL27864169 | 0.86 | — | — | |
| SCHEMBL1729349 | 0.83 | ALDH1A1 (0.65) | DNM1TSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8332066 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940421-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-07-09 | — | — | EP | claimed |
| WO-2007032004-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | claimed |
| EP-1934234-B1 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | YISSUM RES DEV CO (IL) | 2011-11-30 | — | — | EP | disclosed |
| US-20100284914-A1 | Novel Amine-Borane Compounds and Uses Thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2010-11-11 | — | — | US | disclosed |
| US-20090131366-A1 | Use of Amine-Borane Compounds as Anti-Microbial Agents | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2009-05-21 | — | — | US | disclosed |
| EP-1940421-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-07-09 | — | — | EP | disclosed |
| EP-1934234-A2 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032004-A1 | USE OF AMINE-BORANE COMPOUNDS AS ANTI-MICROBIAL AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007032005-A2 | NOVEL AMINE-BORANE COMPOUNDS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131366-A1 | Use of Amine-Borane Compounds as Anti-Microbial Agents | BCAT2, BCAT1, ARG1 | DNM1 2204/4885TSHR 2627/4885ALDH1A1 3639/4885 |
| US-20100284914-A1 | Novel Amine-Borane Compounds and Uses Thereof | SLC1A5, BDKRB1, PAICS | DNM1 2564/4885TSHR 1109/4885ALDH1A1 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.