Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993198 | 0.81 | GRN (0.43) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL25455581 | 0.80 | MAPK1 (0.36) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL25453637 | 0.80 | MAPK1 (0.41) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL23051973 | 0.80 | GRN (0.39) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL17219707 | 0.79 | GRN (0.35) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL29750396 | 0.79 | CAD (0.39) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL17291698 | 0.79 | CTSK (0.36) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL23051872 | 0.77 | CTSK (0.38) | MAPK1GRNSORT1CTSKCTSS | |
| SCHEMBL23051981 | 0.77 | GRN (0.40) | MAPK1GRNSORT1CYP1A2CYP2C9 | |
| SCHEMBL20571233 | 0.76 | GRN (0.40) | MAPK1GRNSORT1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200237742-A1 | Serdexmethylphenidate Conjugates, Compositions And Methods Of Use Thereof | COMMAVE THERAPEUTICS SA (CH) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200237742-A1 | Serdexmethylphenidate Conjugates, Compositions And Methods Of Use Thereof | SLC6A3, COMT, SLC6A4 | MAPK1 2799/4885GRN 1266/4885SORT1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.