Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 13/20 | 0.35 |
| ▸ | SKP1 | P63208 | 13/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 13/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729035 | 0.89 | FFAR4 (0.37) | FFAR4PIM2CKS1BSKP1SKP2 | |
| SCHEMBL1729202 | 0.83 | KDM4E (0.46) | — | |
| SCHEMBL1730301 | 0.81 | LMNA (0.38) | AOC3 | |
| SCHEMBL1729037 | 0.80 | HCAR2 (0.46) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL1730309 | 0.79 | CRHBP (0.44) | ACACBACACA | |
| SCHEMBL1730249 | 0.78 | HTR3A (0.42) | CKS1BSKP1SKP2AOC3 | |
| SCHEMBL1730164 | 0.77 | DEGS1 (0.47) | AOC3 | |
| SCHEMBL1730190 | 0.77 | CHRM4 (0.44) | AOC3 | |
| SCHEMBL1727953 | 0.77 | PDE10A (0.45) | — | |
| SCHEMBL1727546 | 0.77 | HSD11B1 (0.39) | CKS1BSKP1SKP2AOC3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |