Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046907 | 0.84 | HTT (0.49) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL8136300 | 0.82 | ALDH1A1 (0.58) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL2317520 | 0.82 | RXRA (0.46) | RXRARXRBRXRGRBP4 | |
| SCHEMBL28642120 | 0.81 | RXRA (0.49) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL30741241 | 0.80 | CA12 (0.48) | CYP1A2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL30741239 | 0.80 | CA12 (0.48) | CYP1A2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3185351 | 0.80 | CA12 (0.48) | CYP1A2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL6763906 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL2044035 | 0.79 | MAPT (0.38) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL19639466 | 0.79 | HTT (0.45) | CYP1A2CYP2D6CYP2C19HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380520-A1 | STRONG BINDING METAL-CHELATING RESINS USING MACROCYCLE MOLECULES | SACHEM, INC. | 2022-12-01 | — | — | US | disclosed |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20110213110-A1 | NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME | JAPAN POLYPROPYLENE CORPORATION (JP) | 2011-09-01 | — | — | US | disclosed |
| US-7915455-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |
| US-7915455-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090143620-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED | 2009-06-04 | — | — | US | disclosed |
| WO-2006030199-A1 | POLYMERISATION CATALYSTS | INEOS EUROPE LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |
| WO-2006030192-A1 | POLYOLEFINS | INEOS EUROPE LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |
| CN-1243735-C | 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-03-01 | — | — | CN | disclosed |
| CN-1733725-A | Process for preparing 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-02-15 | — | — | CN | disclosed |
| EP-1606294-A1 | POLYMERISATION CATALYSTS | Innovene Europe Limited (GB) | 2005-12-21 | — | — | EP | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| WO-2004083221-A1 | POLYMERISATION CATALYSTS | INNOVENE EUROPE LIMITED (GB) | 2004-09-30 | — | — | WO | disclosed |
| CN-1503784-A | 2-iminopyrrolidine derivatives | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CBR3, CBR1 | CYP1A2 14/4885CYP2D6 63/4885CYP2C19 38/4885 |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | CYP1A2 137/4885CYP2D6 138/4885CYP2C19 347/4885 |
| US-20090143620-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | AP1M1, OR10J3, AP2M1 | CYP1A2 2917/4885CYP2D6 2096/4885CYP2C19 3142/4885 |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | CYP1A2 136/4885CYP2D6 135/4885CYP2C19 346/4885 |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | CYP1A2 6/4885CYP2D6 45/4885CYP2C19 28/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | CYP1A2 6/4885CYP2D6 45/4885CYP2C19 28/4885 |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CBR3, CBR1 | CYP1A2 14/4885CYP2D6 63/4885CYP2C19 38/4885 |
| US-20110213110-A1 | NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME | OPRD1, OSTC, COG7 | CYP1A2 1498/4885CYP2D6 943/4885CYP2C19 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.