Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 8/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730240 | 0.90 | SLC6A7 (0.41) | PANK3DGAT1KCNH2RETSLC6A7 | |
| SCHEMBL1729151 | 0.88 | MGLL (0.42) | PANK3DGAT1KCNH2EGLN1AOC3 | |
| SCHEMBL1729088 | 0.86 | PANK3 (0.39) | PANK3DGAT1KCNH2EP300CACNA1H | |
| SCHEMBL1727900 | 0.85 | EGLN1 (0.41) | CACNA1HSLC6A7EGLN1AOC3 | |
| SCHEMBL1729020 | 0.84 | SCN10A (0.38) | PANK3CACNA1HRETCHRM4 | |
| SCHEMBL1728857 | 0.84 | CNR1 (0.42) | SLC6A7AOC3 | |
| SCHEMBL1727881 | 0.82 | CNR2 (0.48) | DGAT1KCNH2RETSLC6A7EGLN1 | |
| SCHEMBL1728823 | 0.78 | SLC6A7 (0.44) | DGAT1SLC6A7AOC3 | |
| SCHEMBL1728917 | 0.78 | SLC6A7 (0.40) | PANK3DGAT1KCNH2RETSLC6A7 | |
| SCHEMBL1729847 | 0.77 | CNR1 (0.43) | SLC6A7SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |