Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | ME2 | P23368 | 2/20 | 0.39 |
| ▸ | ME1 | P48163 | 2/20 | 0.39 |
| ▸ | ME3 | Q16798 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727881 | 0.90 | CNR2 (0.48) | MGLLEGLN1CNR2DGAT1KCNH2 | |
| SCHEMBL1727900 | 0.88 | EGLN1 (0.41) | ME2ME1ME3EGLN1AOC3 | |
| SCHEMBL1729282 | 0.88 | PANK3 (0.40) | EGLN1DGAT1KCNH2AOC3PANK3 | |
| SCHEMBL1729020 | 0.86 | SCN10A (0.38) | MGLLDRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1728999 | 0.86 | MGLL (0.41) | MGLLME2ME1ME3EGLN1 | |
| SCHEMBL1729059 | 0.85 | DGAT1 (0.41) | MGLLEGLN1CNR2DGAT1KCNH2 | |
| SCHEMBL1728983 | 0.83 | CNR1 (0.40) | CNR2DRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1730240 | 0.82 | SLC6A7 (0.41) | MGLLEGLN1DGAT1KCNH2AOC3 | |
| SCHEMBL1728823 | 0.81 | SLC6A7 (0.44) | MGLLDGAT1AOC3 | |
| SCHEMBL1727558 | 0.79 | KCNH2 (0.40) | MGLLEGLN1CNR2DGAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |