Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729020 | 0.89 | SCN10A (0.38) | HRH3PPARACACNA1HDRD4DRD3 | |
| SCHEMBL1729048 | 0.88 | EGLN1 (0.41) | EGLN1ME2ME1ME3KMT2A | |
| SCHEMBL1729151 | 0.88 | MGLL (0.42) | EGLN1ME2ME1ME3RAB9A | |
| SCHEMBL1729282 | 0.85 | PANK3 (0.40) | EGLN1CACNA1HSLC6A7AOC3 | |
| SCHEMBL1729810 | 0.84 | CNR1 (0.42) | HDAC2HSD17B10L3MBTL1HPGDNPSR1 | |
| SCHEMBL1728823 | 0.82 | SLC6A7 (0.44) | SLC6A7AOC3 | |
| SCHEMBL1727881 | 0.82 | CNR2 (0.48) | EGLN1KMT2ASLC6A7AOC3DRD2 | |
| SCHEMBL1730240 | 0.80 | SLC6A7 (0.41) | EGLN1SLC6A7AOC3 | |
| SCHEMBL1728061 | 0.80 | CACNA1G (0.38) | KMT2AHRH3PPARACACNA1HACACB | |
| SCHEMBL1730220 | 0.79 | EGLN1 (0.45) | EGLN1KMT2AHSD17B10ERN1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |