Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729282 | 0.90 | PANK3 (0.40) | SLC6A7AOC3DGAT1KCNH2RET | |
| SCHEMBL1728917 | 0.88 | SLC6A7 (0.40) | SLC6A7AOC3METUSP30DGAT1 | |
| SCHEMBL1727881 | 0.87 | CNR2 (0.48) | SLC6A7AOC3DGAT1KCNH2MGLL | |
| SCHEMBL1729847 | 0.85 | CNR1 (0.43) | SLC6A7USP30PDE4DPDE4APDE4B | |
| SCHEMBL1728823 | 0.83 | SLC6A7 (0.44) | SLC6A7AOC3DGAT1PDE4DPDE4A | |
| SCHEMBL1729151 | 0.82 | MGLL (0.42) | AOC3DGAT1KCNH2MGLLPANK3 | |
| SCHEMBL1728857 | 0.80 | CNR1 (0.42) | SLC6A7AOC3 | |
| SCHEMBL1727900 | 0.80 | EGLN1 (0.41) | SLC6A7AOC3EGLN1 | |
| SCHEMBL1729020 | 0.78 | SCN10A (0.38) | MGLLRETPANK3 | |
| SCHEMBL1729088 | 0.78 | PANK3 (0.39) | SLC6A7USP30DGAT1KCNH2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |