SCHEMBL17293164

SCHEMBL17293164

FC(F)(F)c1cc(C2=C[CH]c3ccccc32)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
TACR1 P25103 7/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
KIF11 P52732 1/20 0.34
GPR3 P46089 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
PTAFR P25105 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521494 0.87 PTAFR (0.43) CNR2ALDH1A1TSHRPTAFRKDM4E
SCHEMBL28515991 0.84 KIF11 (0.48) CYP1A2POLBCYP2C19ALDH1A1TSHR
SCHEMBL18763978 0.83 RXRB (0.38) MEN1KMT2AALDH1A1KIF11RXRA
SCHEMBL28025517 0.77 CNR1 (0.33) CNR1CNR2CYP1A2TDP1HTR1A
SCHEMBL28025932 0.75 ALOX5AP (0.30)
SCHEMBL28219408 0.74 ALDH1A1 (0.36) MEN1KMT2AHPGDSMN1; SMN2NPSR1
SCHEMBL28025943 0.73 KIF11 (0.44) ALDH1A1KIF11RXRARXRBPTAFR
SCHEMBL5076754 0.73 ALDH1A1 (0.41) HPGDALDH1A1TDP1
SCHEMBL28025423 0.73 BRD9 (0.34) MEN1KMT2ATSHRMAPTHTR1A
SCHEMBL28025959 0.73 PTPRC (0.46) CNR1CNR2TSHRRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
EP-3148937-B1 METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME BRIDGESTONE CORP (JP) 2019-09-18 EP disclosed
US-10017595-B2 Metallic complex catalyst and polymerization methods employing same BRIDGESTONE CORPORATION (JP) 2018-07-10 US disclosed
US-20170114171-A1 Metallic Complex Catalyst And Polymerization Methods Employing Same BRIDGESTONE CORPORATION (JP) 2017-04-27 US disclosed
EP-3148937-A1 METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME Bridgestone Corporation (JP) 2017-04-05 EP disclosed
WO-2015183770-A1 METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME BRIDGESTONE CORPORATION (JP) 2015-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170114171-A1 Metallic Complex Catalyst And Polymerization Methods Employing Same C5, C1S, C9 CNR1 630/4885CNR2 335/4885TACR1 3084/4885
US-10017595-B2 Metallic complex catalyst and polymerization methods employing same C5, C1S, C9 CNR1 630/4885CNR2 335/4885TACR1 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.