Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | ACACA | Q13085 | 6/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727890 | 0.88 | HTR1A (0.40) | HTR1AACACBACACAP2RX7KCNH2 | |
| SCHEMBL1727953 | 0.87 | PDE10A (0.45) | HTR1AHTR3AHRH3PDE10A | |
| SCHEMBL1728230 | 0.86 | PDE10A (0.45) | PTPN11PDE10A | |
| SCHEMBL1730416 | 0.83 | HRH3 (0.47) | HTR1AACACBACACAKCNH2HTR3A | |
| SCHEMBL1727924 | 0.83 | HRH3 (0.48) | HTR1AACACBKCNH2HTR3AHRH3 | |
| SCHEMBL1729037 | 0.81 | HCAR2 (0.46) | ACACBACACAHTR3APDE10A | |
| SCHEMBL1727546 | 0.81 | HSD11B1 (0.39) | ACACBACACAKCNH2HTR3A | |
| SCHEMBL1727572 | 0.79 | CNR1 (0.41) | HTR1A | |
| SCHEMBL239521 | 0.79 | P2RX7 (0.48) | HTR1AACACBACACAP2RX7PTPN11 | |
| SCHEMBL1730164 | 0.79 | DEGS1 (0.47) | KCNH2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |