Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 8/20 | 0.43 |
| ▸ | SKP1 | P63208 | 8/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 8/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727953 | 0.88 | PDE10A (0.45) | ALDH1A1HTTSMN1; SMN2PDE10ADPP4 | |
| SCHEMBL1730192 | 0.87 | CKS1B (0.46) | HCAR2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL1729269 | 0.85 | AKR1C3 (0.45) | HTR3A | |
| SCHEMBL1730249 | 0.84 | HTR3A (0.42) | SMN1; SMN2CKS1BSKP1SKP2HTR3A | |
| SCHEMBL1729610 | 0.81 | HTR1A (0.40) | PDE10AHTR3AACACBACACA | |
| SCHEMBL1728019 | 0.80 | FFAR4 (0.36) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL1727572 | 0.80 | CNR1 (0.41) | CKS1BSKP1SKP2 | |
| SCHEMBL1730164 | 0.79 | DEGS1 (0.47) | MAPTSMN1; SMN2PDE10A | |
| SCHEMBL1730190 | 0.79 | CHRM4 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL1727546 | 0.79 | HSD11B1 (0.39) | NFKB1CKS1BSKP1SKP2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |