Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728232 | 0.87 | PTGES (0.41) | HTR3ALMNAHTT | |
| SCHEMBL1727957 | 0.87 | KDM4E (0.45) | HTR1AHTR3AHRH3LMNAHTT | |
| SCHEMBL1727892 | 0.86 | HTR1A (0.39) | HTR1AP2RX7HTR3AHRH3MAPT | |
| SCHEMBL1730418 | 0.84 | HRH3 (0.45) | HTR1AP2RX7HTR3AHRH3 | |
| SCHEMBL1727926 | 0.83 | HRH3 (0.46) | HTR1AHTR3AHRH3LMNA | |
| SCHEMBL1729040 | 0.83 | HCAR2 (0.46) | HTR3AMAPTLMNAHTT | |
| SCHEMBL1727545 | 0.82 | GRIN2D (0.36) | HTR3AHRH3 | |
| SCHEMBL1727570 | 0.80 | CNR1 (0.39) | HTR1A | |
| SCHEMBL1730161 | 0.80 | DEGS1 (0.43) | HTR1AMAPT | |
| SCHEMBL1729221 | 0.78 | HRH3 (0.48) | HRH3MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |