Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727648 | 0.90 | MAPT (0.34) | P2RX7MAPTKDM4EALDH1A1HTR3A | |
| SCHEMBL1727901 | 0.88 | SETDB1 (0.38) | MAPTHRH3KDM4EALDH1A1HCAR2 | |
| SCHEMBL1729592 | 0.88 | PTGES (0.42) | SMO | |
| SCHEMBL1728165 | 0.87 | KDM4E (0.45) | HRH3KDM4EALDH1A1HTR3AHCAR2 | |
| SCHEMBL1729611 | 0.86 | HTR1A (0.39) | HTR1AP2RX7MAPTHRH3HTR3A | |
| SCHEMBL1729370 | 0.86 | HRH3 (0.43) | P2RX7HRH3SMOKDM4EALDH1A1 | |
| SCHEMBL1728881 | 0.85 | HCAR2 (0.36) | MAPTSMOKDM4EALDH1A1HCAR2 | |
| SCHEMBL1727724 | 0.84 | HSD11B1 (0.40) | HRH3 | |
| SCHEMBL1729308 | 0.84 | HRH3 (0.44) | HTR1AHRH3HTR3A | |
| SCHEMBL1730195 | 0.84 | HCAR2 (0.46) | MAPTALDH1A1HTR3AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |