Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728645 | 0.90 | CNR1 (0.50) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1727657 | 0.85 | CNR1 (0.54) | CNR1DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1727411 | 0.83 | DRD4 (0.47) | DRD3HTR1AHTR2ACCR3DRD2 | |
| SCHEMBL1727960 | 0.82 | DRD4 (0.56) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1727728 | 0.80 | CNR1 (0.47) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1727394 | 0.80 | HTR1A (0.46) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1729843 | 0.79 | CNR1 (0.44) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1728845 | 0.79 | CNR1 (0.45) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1728049 | 0.78 | DRD4 (0.51) | CNR1DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1727631 | 0.75 | HTR1A (0.48) | DRD3HTR1AHTR2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |