Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727978 | 0.90 | KDM1A (0.43) | KDM1AHRH3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1730318 | 0.87 | HRH3 (0.43) | KDM1AHRH3SMN1; SMN2LMNAKMT2A | |
| SCHEMBL1727687 | 0.85 | PDE10A (0.43) | KDM1ASMN1; SMN2LMNAKMT2APPARG | |
| SCHEMBL1728906 | 0.85 | DEGS1 (0.48) | KDM1ASMN1; SMN2MAPTLMNATNF | |
| SCHEMBL1729795 | 0.82 | LMNA (0.60) | SMN1; SMN2MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL1729679 | 0.82 | CHRM4 (0.48) | — | |
| SCHEMBL1727662 | 0.81 | HTR1A (0.43) | KDM1ALMNAAOC3 | |
| SCHEMBL1729166 | 0.80 | LMNA (0.39) | KDM1ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL19598739 | 0.78 | HRH3 (0.54) | KDM1AHRH3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19598748 | 0.76 | HRH3 (0.52) | KDM1AHRH3SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |