Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 6/20 | 0.45 |
| ▸ | JAK3 | P52333 | 6/20 | 0.45 |
| ▸ | JAK1 | P23458 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727687 | 0.84 | PDE10A (0.43) | CHRM4PANK3 | |
| SCHEMBL1730318 | 0.84 | HRH3 (0.43) | PANK3GPR119 | |
| SCHEMBL1728906 | 0.84 | DEGS1 (0.48) | KCNH2GPR119 | |
| SCHEMBL30549291 | 0.82 | PANK3 (0.53) | CHRM4DPP4PANK3JAK2JAK3 | |
| SCHEMBL2225824 | 0.82 | PANK3 (0.53) | CHRM4DPP4PANK3JAK2JAK3 | |
| SCHEMBL1729359 | 0.82 | KDM1A (0.45) | — | |
| SCHEMBL1729795 | 0.81 | LMNA (0.60) | CHRM4DPP4JAK2JAK3DPP8 | |
| SCHEMBL1727662 | 0.80 | HTR1A (0.43) | CHRM4KCNH2 | |
| SCHEMBL13622620 | 0.79 | KCNH2 (0.55) | CHRM4DPP4PANK3JAK2JAK3 | |
| SCHEMBL1729166 | 0.77 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |