SCHEMBL17298935

SCHEMBL17298935

C=CC(CCC)NC(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7678905 0.76 CTSK (0.37) TDP1
SCHEMBL19008276 0.74 KISS1R (0.34)
SCHEMBL18643032 0.73
SCHEMBL25157049 0.70 TDP1 (0.30) TDP1
SCHEMBL15375249 0.70 TSHR (0.41)
SCHEMBL9418800 0.70
SCHEMBL27855255 0.68 TSHR (0.33)
SCHEMBL18570868 0.67 ADH1B (0.43)
SCHEMBL11523628 0.67 PLA2G2C (0.39) TDP1
SCHEMBL21477642 0.67 TSHR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170044095-A1 COMPOUNDS FOR THE TREATMENT OF SEIZURES AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS AND CONDITIONS Ketogen, Inc. (CA) 2017-02-16 US disclosed
US-9481637-B2 Compounds for the treatment of seizures and other central nervous systems disorders and conditions Ketogen Inc. (CA) 2016-11-01 US disclosed
US-20150344413-A1 COMPOUNDS FOR THE TREATMENT OF SEIZURES AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS AND CONDITIONS Ketogen Inc. (CA) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044095-A1 COMPOUNDS FOR THE TREATMENT OF SEIZURES AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS AND CONDITIONS PC, PYGB, GLS2 TDP1 2922/4885MMP9 4226/4885
US-20150344413-A1 COMPOUNDS FOR THE TREATMENT OF SEIZURES AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS AND CONDITIONS PC, PYGB, GLS2 TDP1 2922/4885MMP9 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.