Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706255 | 0.72 | ADRA1D (0.46) | KDM4EAPAF1ALDH1A1POLBMAPT | |
| SCHEMBL12775191 | 0.70 | POLB (0.56) | KDM4EAPAF1ALDH1A1POLBMAPT | |
| SCHEMBL1729633 | 0.68 | SMYD3 (0.42) | — | |
| SCHEMBL6774386 | 0.65 | KDM4E (0.46) | KDM4EAPAF1ALDH1A1POLBMAPT | |
| SCHEMBL1728966 | 0.65 | MAOA (0.46) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL1728792 | 0.65 | AKT1 (0.42) | ALDH1A1HPGD | |
| SCHEMBL20267079 | 0.65 | ADRA1B (0.58) | ADRA1DADRA1AADRA1B | |
| SCHEMBL1729018 | 0.64 | SMYD3 (0.43) | — | |
| SCHEMBL1727781 | 0.64 | SMYD3 (0.43) | — | |
| SCHEMBL11398578 | 0.64 | KDM4E (0.65) | KDM4EAPAF1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |