Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18703937 | 0.88 | STS (0.43) | GPR119MAPTKDM4ETHRBEPHX2 | |
| SCHEMBL12713082 | 0.83 | ALDH1A1 (0.47) | GPR119KMT2ATP53MAPTKDM4E | |
| SCHEMBL19013246 | 0.77 | GPR119 (0.55) | GPR119KMT2ATP53MAPTKDM4E | |
| SCHEMBL13941529 | 0.77 | GPR119 (0.46) | GPR119KMT2ATP53MAPTKDM4E | |
| SCHEMBL12713081 | 0.76 | GPR119 (0.57) | GPR119KMT2ATP53MAPTKDM4E | |
| SCHEMBL23721774 | 0.74 | TGFBR1 (0.45) | GPR119MAPTKDM4ETHRBEPHX2 | |
| SCHEMBL3549233 | 0.74 | GPR119 (0.55) | GPR119KMT2ATP53MAPTKDM4E | |
| SCHEMBL17477303 | 0.74 | GPR119 (0.48) | GPR119KMT2AMAPTKDM4ETHRB | |
| SCHEMBL12713087 | 0.74 | SMN1; SMN2 (0.48) | TP53MAPTKDM4ELMNA | |
| SCHEMBL12713105 | 0.73 | SMN1; SMN2 (0.49) | TP53MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182723-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2015-12-03 | — | — | WO | disclosed |