Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593734 | 0.92 | SIGMAR1 (0.62) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL29756483 | 0.92 | SIGMAR1 (0.62) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2923966 | 0.90 | SIGMAR1 (0.61) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL28849168 | 0.86 | CXCR4 (0.64) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL29863040 | 0.86 | CXCR4 (0.64) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL10892692 | 0.86 | HRH3 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL29168432 | 0.81 | LMNA (0.71) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL17308221 | 0.81 | CXCR4 (0.66) | MEN1POLBKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL26789 | 0.80 | SIGMAR1 (0.78) | MEN1KMT2ASIGMAR1ALDH1A1HRH3 | |
| SCHEMBL21009691 | 0.80 | MEN1 (0.65) | MEN1POLBKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | MEN1 3091/4885POLB 1295/4885KMT2A 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.