Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27713050 | 0.98 | SIGMAR1 (0.75) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL24271305 | 0.96 | SIGMAR1 (0.79) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL28208414 | 0.89 | CXCR4 (0.61) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL152631 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL6138636 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| Benzene SCHEMBL27761330 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL83548 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL276363 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL1618521 | 0.87 | SIGMAR1 (0.59) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL2223234 | 0.86 | SIGMAR1 (0.96) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776849-B2 | Benzenoid ansamycin derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-08-17 | — | — | US | claimed |
| EP-1064268-B1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2005-11-30 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1064267-B1 | NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2004-09-29 | — | — | EP | claimed |
| EP-1066246-B1 | NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING | OREAL (FR) | 2003-11-05 | — | — | EP | claimed |
| EP-1066022-B1 | COMPOSITIONS FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC COUPLER, NOVEL CATIONIC COUPLERS, THEIR USE FOR OXIDATION DYEING AND DYEING METHODS | OREAL (FR) | 2003-10-22 | — | — | EP | claimed |
| EP-1341761-A1 | SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-$g(g) BINDING AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-10 | — | — | EP | claimed |
| US-6605124-B1 | Naphthol hair dyes for keratinous fibers | L'OREAL S.A. (FR) | 2003-08-12 | — | — | US | claimed |
| US-20030087902-A1 | Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents | SMITHKLINE BEECHAM CORPORATION | 2003-05-08 | — | — | US | claimed |
| US-6544298-B1 | Dyeing human hair using coupler | L'OREAL (FR) | 2003-04-08 | — | — | US | claimed |
| EP-1064268-A1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2001-01-03 | — | — | EP | claimed |
| WO-2000042979-A1 | COMPOSITIONS FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC COUPLER, NOVEL CATIONIC COUPLERS, THEIR USE FOR OXIDATION DYEING AND DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| WO-2000043368-A1 | NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| WO-2000042971-A2 | NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| WO-2000043356-A1 | NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| WO-1999048874-A1 | NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-09-30 | — | — | WO | claimed |
| WO-1999048875-A1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-09-30 | — | — | WO | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087902-A1 | Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents | PPARG, PPARA, PPARD | SIGMAR1 2189/4885KMT2A 2753/4885ALDH1A1 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.