Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309763 | 0.90 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL7877088 | 0.89 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL30506112 | 0.89 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL17309756 | 0.88 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL17309764 | 0.88 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL554352 | 0.86 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28843221 | 0.85 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL7982231 | 0.85 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1880444 | 0.85 | KDM4E (0.46) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL9250127 | 0.84 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952184-B1 | Pharmaceutical formulation for treating pancreatic cancer | UNIV CHINA MEDICAL (TW) | 2019-06-05 | — | — | EP | disclosed |
| US-9872912-B2 | Method for treating pancreatic cancer | CHINA MEDICAL UNIVERSITY (TW) | 2018-01-23 | — | — | US | disclosed |
| US-20150352213-A1 | METHOD FOR TREATING PANCREATIC CANCER | EVERFRONT BIOTECH INC. (TW) | 2015-12-10 | — | — | US | disclosed |
| EP-2952184-A1 | Pharmaceutical formulation for treating pancreatic cancer | China Medical University (TW) | 2015-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352213-A1 | METHOD FOR TREATING PANCREATIC CANCER | RNASE1, PNLIP, AMY2A | KDM4E 1875/4885KMT2A 3163/4885MEN1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.