SCHEMBL17313675

SCHEMBL17313675

C=Cc1cccc2ccccc12.ClCC=Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.43
DRD2 P14416 1/20 0.43
ADRA2C P18825 1/20 0.43
CNR1 P21554 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
ADRA1A P35348 1/20 0.43
OPRK1 P41145 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KCNH2 Q12809 1/20 0.43
EBP Q15125 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451576 0.89 ALDH1A1 (0.43) HTR2ATSHRPAM
Styrene SCHEMBL9488136 0.85 ALDH1A1 (0.50) HTR2ATSHRPAM
SCHEMBL10558462 0.85 NR1I2 (0.46) NR1I2DRD2ADRA2CCNR1SLC6A2
SCHEMBL10457001 0.83 CHAT (0.44) TSHRCHATHDAC8HDAC6
SCHEMBL15421494 0.81 HTR2A (0.38) HTR2ASIGMAR1MEN1TSHRKMT2A
SCHEMBL8175856 0.80 RXRA (0.49) CYP1A2CYP2D6CHATHDAC8HDAC6
SCHEMBL7006267 0.80 RXRA (0.49) CYP1A2CYP2D6CHATHDAC8HDAC6
Styrene SCHEMBL138405 0.80 ALDH1A1 (0.56) MEN1TSHRKMT2ACHATHDAC8
SCHEMBL10951988 0.80 CHAT (0.44) TSHRCHATHDAC8HDAC6
SCHEMBL6169645 0.80 CHAT (0.47) NR1I2DRD2ADRA2CCNR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190077894-A1 PROCESS FOR PREPARING CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2019-03-14 US claimed
US-20150353660-A1 PROCESS FOR PREPARING CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2015-12-10 US claimed
US-9006457-B2 Reactive ionic liquids BASF SE (DE) 2015-04-14 US disclosed