SCHEMBL451576

SCHEMBL451576

C=Cc1ccccc1C=C.ClCC=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 1/20 0.43
IDO1 P14902 2/20 0.41
PAM P19021 1/20 0.41
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
HTR2A P28223 3/20 0.39
TRPA1 O75762 1/20 0.38
NFE2L2 Q16236 1/20 0.38
MAOB P27338 1/20 0.38
POLB P06746 2/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36
RAB9A P51151 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9488136 0.96 ALDH1A1 (0.50) ALDH1A1TSHRIDO1PAMPTGER4
SCHEMBL15421494 0.92 HTR2A (0.38) ALDH1A1TSHRIDO1PAMPTGER4
SCHEMBL17313675 0.89 NR1I2 (0.43) TSHRPAMHTR2A
Styrene SCHEMBL1507248 0.88 ALDH1A1 (0.58) ALDH1A1TSHRIDO1PAMHTR2A
SCHEMBL308354 0.88 ALDH1A1 (0.38) ALDH1A1TSHRIDO1PAMPTGER4
SCHEMBL15852 0.85 IDO1 (0.52) IDO1PAMHTR2AMAOBNPC1
SCHEMBL39674 0.85 IDO1 (0.52) IDO1PAMHTR2AMAOBNPC1
SCHEMBL9044783 0.85 IDO1 (0.52) IDO1PAMHTR2AMAOBNPC1
Benzene SCHEMBL1225975 0.85 IDO1 (0.52) IDO1PAMHTR2AMAOBNPC1
Benzene SCHEMBL1225972 0.85 IDO1 (0.52) IDO1PAMHTR2AMAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115477625-B Method for preparing 5-hydroxymethylfurfural 中国石油化工股份有限公司 2024-05-17 CN claimed
CN-117907477-A Water-soluble ion detection and analysis method 浙江杭康检测技术有限公司 2024-04-19 CN claimed
CN-116472636-A Nonaqueous redox flow battery 埃尼股份公司 2023-07-21 CN claimed
CN-115477625-A Method for preparing 5-hydroxymethylfurfural 中国石油化工股份有限公司 2022-12-16 CN claimed
CN-110026161-B Polymer-based nano lanthanum oxide hydrate material, crystal form and crystallinity regulating and controlling method, application and regeneration method 南京大学 2022-03-15 CN claimed
EP-3482441-B1 NON-AQUEOUS REDOX FLOW BATTERIES ENI SPA (IT) 2020-06-17 EP claimed
US-4405418-A PURIFICATION OF SODIUM CHLORIDE ELECTROLYTE WITH CHELATING ION EXCHANGE RESIN OF CROSSLINKED CHLOROMETHYLSTYRENE-DIVINYLBENZENE COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-09-20 US claimed
JP-56123387-A None JP disclosed
CN-118251230-A Inhibition of neurodegeneration with zinc transporter 7 加利福尼亚大学董事会 2024-06-25 CN disclosed
US-20240199663-A1 Cyclopolyphosphazenes, Related Methods of Preparation and Methods of Use UNITED STATES DEPARTMENT OF ENERGY 2024-06-20 US disclosed
EP-4384202-A1 SUPPRESSION OF NEURODEGENERATION WITH ZINC TRANSPORTER PROTEIN 7 The Regents of the University of California (US) 2024-06-19 EP disclosed
EP-4380953-A2 RABBIT HAEMORRHAGIC DISEASE VIRUS (RHDV) VACCINES VST LLC dba Medgene Labs (US) 2024-06-12 EP disclosed
CN-115477625-B Method for preparing 5-hydroxymethylfurfural 中国石油化工股份有限公司 2024-05-17 CN disclosed
EP-0335637-A2 Nerve growth factor peptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1989-10-04 EP disclosed
US-4705778-A LUTEINIZING HORMONE RELEASING HORMONE SRI INTERNATIONAL (US) 1987-11-10 US disclosed
US-4599175-A CHELATING RESIN ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-07-08 US disclosed
US-4405418-A PURIFICATION OF SODIUM CHLORIDE ELECTROLYTE WITH CHELATING ION EXCHANGE RESIN OF CROSSLINKED CHLOROMETHYLSTYRENE-DIVINYLBENZENE COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-09-20 US disclosed
JP-S56123387-A PRODUCTION OF SODIUM CHLORATE ASAHI CHEM IND CO LTD 1981-09-28 JP disclosed
US-4243638-A Iron EDTA chelate catalyzed oxidation of uranium WESTINGHOUSE ELECTRIC CORP. (US) 1981-01-06 US disclosed
US-4155982-A USING AMMONIA, HYDROGEN PEROXIDE AND AMMONIUM BICARBONATE WYOMING MINERAL CORPORATION (US) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199663-A1 Cyclopolyphosphazenes, Related Methods of Preparation and Methods of Use PHOSPHO1, TOP2B, TOP2A ALDH1A1 2802/4885TSHR 4008/4885IDO1 1502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.