Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.46 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756272 | 0.84 | AGXT (0.52) | HDAC4MEF2DAGXTLMNAPIM1 | |
| SCHEMBL13996557 | 0.83 | ADRA2C (0.56) | AGXTPLOD2PLOD3PLOD1L3MBTL1 | |
| SCHEMBL108137 | 0.82 | LMNA (0.53) | AGXTLMNAPIM1KMOHDAC3 | |
| SCHEMBL3089631 | 0.82 | VSIR (0.52) | HDAC4MEF2DAGXTLMNAPIM1 | |
| SCHEMBL6992776 | 0.82 | LMNA (0.57) | HDAC4MEF2DAGXTLMNAPIM1 | |
| SCHEMBL4368142 | 0.82 | GAA (0.62) | LMNAPOLBNPC1GAARAB9A | |
| SCHEMBL21966131 | 0.81 | LMNA (0.49) | HDAC4MEF2DAGXTLMNAPIM1 | |
| SCHEMBL8985943 | 0.81 | ADRB1 (0.57) | HDAC4MEF2DMAPT | |
| SCHEMBL1964227 | 0.81 | HDAC4 (0.60) | HDAC4MEF2DAGXTLMNAPIM1 | |
| Hydrochloric Acid SCHEMBL2470828 | 0.81 | VSIR (0.51) | HDAC4MEF2DAGXTLMNAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| WO-2015187684-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | HDAC4 3311/4885MEF2D 968/4885AGXT 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.