Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201905 | 0.87 | KDM4E (0.75) | GPR84HTR1DHTR1AHTR1BKDM4E | |
| SCHEMBL15747709 | 0.87 | KDM4E (0.75) | GPR84HTR1DHTR1AHTR1BKDM4E | |
| SCHEMBL15747748 | 0.86 | KDM4E (0.59) | GPR84HTR1DHTR1AHTR1BHTR2B | |
| SCHEMBL17320607 | 0.85 | KDM4E (0.69) | GPR84HTR1DHTR1AHTR1BKDM4E | |
| SCHEMBL178561 | 0.84 | GPR84 (0.78) | GPR84HTR1DHTR1AHTR1BHTR2B | |
| SCHEMBL2007192 | 0.84 | TRPM8 (0.72) | HTR1DHTR1AHTR1BKDM4ETRPM8 | |
| SCHEMBL24493816 | 0.78 | PPARG (0.65) | HTR1DHTR1AHTR1BKDM4ETRPM8 | |
| SCHEMBL23269429 | 0.78 | HTR1B (0.61) | GPR84HTR1DHTR1AHTR1BHTR2B | |
| SCHEMBL23269931 | 0.77 | HTR1B (0.71) | GPR84HTR1DHTR1AHTR1BKDM4E | |
| SCHEMBL24493808 | 0.77 | PPARG (0.68) | HTR1DHTR1AHTR1BKDM4ETRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353489-A1 | Erythropoietin Expression Promoter | EPOR, NFE2L2, FOXO1 | GPR84 1199/4885HTR1D 4194/4885HTR1A 3553/4885 |
| US-10004718-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | GPR84 1199/4885HTR1D 4194/4885HTR1A 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.