Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747709 | 0.90 | KDM4E (0.75) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL30201905 | 0.90 | KDM4E (0.75) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL17320596 | 0.89 | KDM4E (0.53) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL30176255 | 0.87 | LTA4H (0.64) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL853597 | 0.87 | LTA4H (0.64) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL2686551 | 0.87 | KDM4E (0.77) | KDM4EMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL23701834 | 0.86 | PPARG (0.68) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL17320604 | 0.86 | GPR84 (0.57) | KDM4EHTR1ACYP2D6CYP1A2HTR2B | |
| SCHEMBL17320607 | 0.84 | KDM4E (0.69) | KDM4EPPARGPPARDPPARAMTNR1A | |
| SCHEMBL23701738 | 0.84 | PPARG (0.59) | KDM4EPPARGPPARDPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12139459-B2 | Enhancer of fertilization function of sperm | TOHOKU UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | TOHOKU UNIVERSITY (JP) | 2019-07-25 | — | — | US | disclosed |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | TOHOKU UNIVERSITY (JP) | 2019-07-25 | — | — | US | disclosed |
| US-20180353475-A1 | Erythropoietin Expression Promoter | KAKE EDUCATIONAL INSTITUTION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-2923700-B1 | ERYTHROPOIETIN EXPRESSION PROMOTER | UNIV TOHOKU (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2923700-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | Tohoku University (JP) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014080640-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | 国立大学法人東北大学 (JP) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180353475-A1 | Erythropoietin Expression Promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
| US-12139459-B2 | Enhancer of fertilization function of sperm | CATSPER1, NASP, ZP1 | KDM4E 2497/4885PPARG 2757/4885PPARD 3898/4885 |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | SLC26A4, OTC, SLC25A20 | KDM4E 4657/4885PPARG 3590/4885PPARD 4217/4885 |
| US-20150353489-A1 | Erythropoietin Expression Promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | CATSPER1, NASP, ZP1 | KDM4E 2497/4885PPARG 2757/4885PPARD 3898/4885 |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | SLC26A4, OTC, SLC25A20 | KDM4E 4657/4885PPARG 3590/4885PPARD 4217/4885 |
| US-10004718-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
| US-10463647-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.