Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298805 | 1.00 | THRB (0.41) | THRBAPPYWHAGCA1CA2 | |
| SCHEMBL1299063 | 0.92 | THRB (0.52) | THRBYWHAGCA1CA2L3MBTL1 | |
| SCHEMBL1299066 | 0.92 | THRB (0.52) | THRBYWHAGCA1CA2L3MBTL1 | |
| SCHEMBL15654088 | 0.90 | APP (0.37) | THRBAPPYWHAGCA1CA2 | |
| SCHEMBL15654086 | 0.89 | APP (0.34) | THRBAPPYWHAGCA1CA2 | |
| SCHEMBL15654090 | 0.89 | APP (0.34) | THRBAPPYWHAGCA1CA2 | |
| SCHEMBL14603427 | 0.82 | PPARA (0.50) | THRBL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL16693261 | 0.81 | L3MBTL1 (0.39) | APPL3MBTL1MAPTMAPK1TYR | |
| SCHEMBL373648 | 0.81 | L3MBTL1 (0.39) | APPL3MBTL1MAPTMAPK1TYR | |
| SCHEMBL30161220 | 0.80 | APP (0.60) | THRBAPPYWHAGMAPTMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564245-B1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC (CH) | 2021-01-27 | — | — | EP | claimed |
| CN-103026267-B | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG | 2015-04-29 | — | — | CN | claimed |
| EP-2526153-B1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2014-04-30 | — | — | EP | claimed |
| CN-103026267-A | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG | 2013-04-03 | — | — | CN | claimed |
| US-8329775-B2 | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-12-11 | — | — | US | claimed |
| US-8262948-B2 | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | claimed |
| US-20110266505-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC. (CH) | 2011-11-03 | — | — | US | claimed |
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | US | claimed |
| WO-2011088449-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | WO | claimed |
| EP-3638705-B1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| EP-2564245-B1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC (CH) | 2021-01-27 | — | — | EP | disclosed |
| US-20200405474-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON RESEARCH, LTD. | 2020-12-31 | — | — | US | disclosed |
| US-10806566-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2020-10-20 | — | — | US | disclosed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | disclosed |
| US-20110266505-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC. (CH) | 2011-11-03 | — | — | US | disclosed |
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | CRY1, CRY2, CRYAA | THRB 3794/4885APP 2176/4885YWHAG 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.