Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 8/20 | 0.37 |
| ▸ | METAP1 | P53582 | 8/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26897366 | 0.83 | CTSC (0.34) | METAP2METAP1SLC7A5NOS2NOS1 | |
| SCHEMBL2128359 | 0.80 | SLC7A5 (0.54) | METAP2METAP1SLC7A5NOS2NOS1 | |
| SCHEMBL25471938 | 0.80 | METAP2 (0.38) | METAP2METAP1SLC7A5NOS2NOS1 | |
| SCHEMBL23085771 | 0.80 | SLC7A5 (0.54) | METAP2METAP1SLC7A5NOS2NOS1 | |
| SCHEMBL20792012 | 0.79 | GABRP (0.36) | SLC7A5BHMTBHMT2SLC1A3SLC1A2 | |
| SCHEMBL18822659 | 0.79 | METAP2 (0.41) | METAP2METAP1NOS2NOS1NOS3 | |
| SCHEMBL18213758 | 0.79 | NOS2 (0.32) | SLC7A5NOS2NOS1NOS3ARG1 | |
| SCHEMBL15744932 | 0.77 | GABRP (0.34) | SLC7A5BHMTBHMT2SLC1A3SLC1A2 | |
| SCHEMBL24701919 | 0.77 | METAP2 (0.40) | METAP2METAP1SLC7A5NOS2NOS1 | |
| SCHEMBL24256521 | 0.76 | METAP2 (0.36) | METAP2METAP1SLC7A5SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9764037-B2 | Conjugate compounds | VICTORIA LINK LIMITED (NZ) | 2017-09-19 | — | — | US | disclosed |
| US-9764037-B2 | Conjugate compounds | VICTORIA LINK LIMITED (NZ) | 2017-09-19 | — | — | US | disclosed |
| US-20170119875-A1 | AMINO SPHINGOGLYCOLIPID ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2017-05-04 | — | — | US | disclosed |
| US-20170119875-A1 | AMINO SPHINGOGLYCOLIPID ANALOGUES | VICTORIA LINK LIMITED (NZ) | 2017-05-04 | — | — | US | disclosed |
| US-20150352219-A1 | CONJUGATE COMPOUNDS | VICTORIA LINK LIMITED (NZ) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119875-A1 | AMINO SPHINGOGLYCOLIPID ANALOGUES | SGMS1, ENPP2, SGMS2 | METAP2 156/4885METAP1 152/4885SLC7A5 183/4885 |
| US-20150352219-A1 | CONJUGATE COMPOUNDS | SGMS1, SGMS2, ENPP2 | METAP2 634/4885METAP1 538/4885SLC7A5 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.